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Adjusting Schedules for Nerve-Related Symptoms If your B12 deficiency has progressed to the point where youre experiencing nerve-related symptoms like tingling or numbness in your hands and feet, your treatment plan will need to be more intensive

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If youre severely deficient, your provider may recommend more frequent injections at firstoften once per week before switching to monthly maintenance doses

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Preclinical studies demonstrate elevated intracellular NAD+ levels following NNMT inhibition, suggesting a role in metabolic energy regulation