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Grade Study Research Group, Nathan DM, Lachin JM, Balasubramanyam A, Burch HB, Buse JB, Butera NM, Cohen RM, Crandall JP, Kahn SE, Krause-Steinrauf H, Larkin ME, Rasouli N, Tiktin M, Wexler DJ, Younes N, The GSRG

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10.3389/fnagi.2018.00411 115 KawasumiM.ChibaT.YamadaM.Miyamae-KanekoM.MatsuokaM.NakaharaJ.et al (2004)

That structural feature is significant: proline residues resist proteolytic cleavage, making the peptide unusually stable in gastric conditions relative to most short peptides [1]