According to the working model, these cysteine residues may undergo chemical modification/remodeling including trisulfide bond formation and/or related reactions, resulting in a regional (minor, but effective) structural alteration that enhances c-met binding and the nitration resistance of Y198-HGF
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Pharmacologic targeting of hypoxia-inducible factors
Elting LS, Whimbey E, Lo W, Couch R, Andreeff M , Bodey GP
Glutathione is often called the bodys master antioxidant, playing a vital role in detoxification, immune health, and protecting cells from oxidative stress