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Metabolic Dysfunction-Associated Steatohepatitis (MASH) Important Safety Information and Contraindications Who Should NOT Use Semaglutide (Contraindications) Common and Serious Side Effects Gastrointestinal Issues: The most common side effects are related to the digestive system

Clinical Associate Professor Brendon Neuen, lead author of the paper, stated, SGLT2 inhibitors have clear protective effects against heart failure and chronic kidney disease, while GLP-1 receptor agonists can reduce the risk of heart attack, stroke, and also kidney disease. [1] This highlights how their distinct mechanisms work together

Side effects are uncommon and generally mild

However, this correlation turned negative when the effects of PC-DHA and LPC-DHA are included, since the latter induce a much greater increase in brain DHA without a concomitant effect on erythrocytes (Fig