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These effects are particularly noticeable in individuals with a B12 deficiency or conditions like chronic fatigue syndrome or anemia, where long-term treatment can significantly improve quality of life

Bone Health If your body lacks B12, your skeleton may suffer: in a study published in the Journal of Bone and Mineral Research (4), low B12 was linked with poor bone mineral density, suggesting a role for the vitamin in bone formation

You might do other things to help with hormonal balance, and you find that nothing helps

Evidence level: Mechanism exceeds clinical evidence How to read this: Cellular NAD+ changes do not establish a human clinical benefit

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