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Lejding T, Engfeldt M, Bruze M, et al Skin application of glutathione and iron sulfate can inhibit elicitation of allergic contact dermatitis from hexavalent chromium Contact Derm

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It's gentle and well-tolerated by most skin types, including sensitive and reactive skin

NAC treatment not only reduced mercury levels in both lung tissue and bloods but also ameliorated histopathological abnormalities and downregulated the expression of inflammation- and oxidative stress-related genes, including MPO , HIF1 , and TIMP1

GSH is synthesiszed via two ATP-dependent processes that are catalysed by -Glu-Cys synthetase (GSH1) and GSH synthetase (GSH2), and it is mostly degraded by -Glutamyl transpeptidases (-GT), which split GSH into cysteinyl-glycine (Cys-Gly) and Glu residue