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Glutathione injection is generally safe and well-tolerated, but minor side effects like redness or discomfort can be seen at the injection site area

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Further DBPC studies using biomarkers of metabolic pathways related to BH 4 metabolism will be needed to determine which children with ASD will most benefit from formulations of BH 4 supplementation like sapropterin

Khoury CK, Bjorkman AD, Dempewolf H, Ramirez-Villegas J, Guarino L, Jarvis A et al (2014) Increasing homogeneity in global food supplies and the implications for food security