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After smoking cessation, the median of daily CLO dose was 200 (75425) mg, the median of plasma CLO concentrations were 482 (2101,174) ng/ml, with 14 (26.4%) patients having plasma CLO concentrations 600 ng/mL, and 2 (3.7%) patients having plasma CLO concentrations 1,000 ng/mL

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California is expected to pass a ballot measure later this year that would legalize recreational use of the drug which currently needs a doctors recommendation