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Both are addictive, and both come with risks

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Other factors include, but are not limited to: 1 Age nicotine clearance decreases with age Sex studies have found women metabolize nicotine and cotinine faster than men Estrogen hormones there is a strong relationship between high estrogen levels, observed in premenopausal women, and increased metabolism of nicotine Smoking tobacco itself can also impact how long nicotine stays in your system

PMID 10639511

(4) quantifying between-study heterogeneity while adjusting for within-study correlation and the number of studies