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Adjusted for age, BMI, alcohol consumption, hiatal hernia, atrophic gastritis and current smoking, FEV1.0: forced expiratory volume in one second Discussion GERD is the most common gastrointestinal disease in Western countries

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The non-neuronal nAChR that contain subunits formed by proteins encoded by CHRNA3 and CHRNA5 are expressed in airway cells (bronchial epithelial cells, neutrophil macrophages, monocytes, and lymphocytes) and are also activated when nicotine enters the lungs, causing the release of proteases, pro-inflammatory cytokines, and oxidants that are responsible for lung remodeling, which leads to lung damage after chronic exposure 176 (Fig

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