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Furthermore, this association is still unclear, as two other studies have shown no difference in spirometric measurements before and after e-cigarette use.[45,46] However, one of these studies did show an increase in pulmonary airflow resistance by impulse oscillometry,[45] which indicates evidence of obstructive airway changes before they can be seen on spirometry

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This can also be performed on joints such as the knees and hands to treat cold bi-syndrome (a condition with symptoms similar to arthritis)

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