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Help your patients take STEPS towards a life free from smoking with NRT: *with the 7 formats Available pharmacotherapies and how they work Nicorette Provides controlled doses of nicotine at lower and slower rates than a cigarette and is available in a variety of formats and flavours to suit patient's preferences NRT has 45+ years of experience 9 Cytisine Cytisine, an alkaloid from the plant cytisus laburnum (golden rain), is a nicotine analogue which acts as a partial nicotinic acetylcholine receptor agonist 12

JTI's global supply chain encompasses multiple approved inner frame suppliers across Japan, Eastern Europe, and Southeast Asia, and the company has been actively involved in sustainability initiatives for tobacco packaging since 2021, including piloting recyclable paperboard inner frame formats across select European markets in 2024 and 2025

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[1] The company's cigarette manufacturing is conducted in its own facility in Greensboro, North Carolina