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While exogenous NAD provides the direct substrate for sirtuin activation and ATP production, 5-Amino-1MQ acts as a membrane-permeable inhibitor of the enzyme Nicotinamide N-methyltransferase (NNMT)

Biotin is a water-soluble vitamin, therefore it is not easily stored in the body

Intramuscular hydroxocobalamin is the preferred treatment for most patients with confirmed deficiency, particularly when malabsorption is present or neurological symptoms exist

However, people who don't have much exposure to sunlight may be deficient in vitamin D

The dose of I-vit 12 Injection depends on your condition, age, weight and other medicines you take, so it must be decided by your doctor