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These chemicals can leach into the soil, contaminating groundwater and local water sources, and negatively affect both human health and aquatic life

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2 Methods 2.1 Literature search PubMed, Web of Science, China National Knowledge Infrastructure (CNKI) were searched, using keywords such as Chronic obstructive pulmonary disease, Mitochondrial dysfunction, Mitochondrial quality control, Mitophagy, Mitochondrial dynamics, Mitochondrial biogenesis, Therapeutic strategies to retrieve studies in ameliorating COPD by targeting mitochondria