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Previous studies have also pointed to long-term smoking as doubling the risk for age-related macular degeneration and as a factor causing lens yellowing and inflammation

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9 The problem is that, right now, its hard to tell how much [THC] you are actually getting when you take a puff of one of these things, Mark Kleiman, who studies marijuana laws and policies at the University of California, Los Angeles, told NPR

As of November 2025 [6] They are predominantly made from Virginia tobacco