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Its a great episode, and, incidentally, the last one written by co-creator Larry David until the series finale two years later

Have you ever seen a movie called The Apple

Nicotine enhances human vascular endothelial cell expression of ICAM-1 and VCAM-1 via protein kinase C, p38 mitogen-activated protein kinase, NF-kappaB, and AP-1

Stress has a well-documented relationship with smoking, and police officers have to cope with it in various forms, including direct risks of being on the job, interruptions to sleeping patterns, working varying shifts, the pressure inherent in the responsibility for protecting citizens, the requirement to control emotions while on the job, seeing so many people in pain and distress and more

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