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Furthermore, both IGF-I and the IGF-IR are expressed in the developing glomerulus and patterns of expression are disrupted in animal models and in human examples of renal disease[140]
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GHSR agonists (ipamorelin) and GHRH analogs (CJC-1295) act through synergistic pituitary signaling pathways, producing GH release 2-5x greater than either peptide alone
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