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Over time, chronic irritation results in excessive keratin deposition on the top layer of the epithelium, which causes a White-corrugated appearance of the mucosa

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We assumed that this bias has increased linearly with time from no bias in the year 2000 (when relatively few adults were wireless-only) [2931] to the level measured in 2011 and used this assumption to calculate corrected estimates in each year from 2001 to 2010

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