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However, it is wise to consult a healthcare professional and follow their instructions if you are suffering from the following health conditions: Heart disease High blood pressure Stomach ulcers Diabetes Asthma Individuals following a sodium-restricted diet or using non-nicotine smoking cessation drugs or anti-depressants should also seek professional guidance before using nicotine gum

(A, B) Relative abundance of differentially abundant bacterial genera in dental microbiome of healthy smokeless tobacco-consuming and non-consuming samples

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Boruta and LEfSe analysis revealed nine significantly discriminating genera based on smokeless tobacco consumption in healthy samples ( Supplementary Figures S5A, B )