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It is hypothesized by some that the zuclomiphene is responsible for some adverse effects associated with clomiphene citrate and that enclomiphene citrate is primarily responsible for the beneficial effects on hypogonadism by increasing FSH and LH

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[52] While elders are more sensitive to GH, and thus more susceptible to the side effects of replacement with rhGH, stimulating production and secretion of endogenous GH with Sermorelin offers the advantage of a more physiological approach to increasing GH pulsatility while reducing risk for side effects

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2011 Oct;211(1):99-106