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References to traditional herbal use are provided only to describe the history and character of mullein leaf and are not a claim that this product provides a medical benefit

The exact nature of these factors (chemical composition) is largely unknown, but constituents which provide reinforcing sensory stimulation and/or minimize excessive irritation from inhaled nicotine are considered to play an important role in non-nicotine effects in cigarette smoke (Rose 2006)

brands were used for comparison

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RYO is a high-margin, high-loyalty category for smoke shops and convenience stores