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Only in rare cases

It is important to identify and understand which EC flavor types are commonly purchased, what their chemical compositions are, and what their potential toxicities are

For example, a daily smoker who switches to nicotine pouches and uses a moderate number of pouches per day might see monthly spending drop from several hundred dollars on cigarettes to a much smaller figure on pouches

Smoking is the cause of more than 70 percent of lung cancer cases, making it the leading cause

While subject compliance with prompts initiated by an electronic diary can easily be measured, compliance with recording of health-relevant events (e.g., asthma attacks, Hensley et al., 2003