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This effect was greatest in the lung cells, but was also noticeable in the mouth, where every cell had an average of 23 mutations per pack year, as well as the bladder and the liver, where cells picked up 18 and six mutations respectively for each year of such excessive smoking

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Additives are important elements of tobacco products because they allow manufacturers to modify the sensory and pharmacological properties of tobacco products in a way that affects initiation and cessation (with additives that make the smoke less harsh or more pleasant to the user) or bioavailability and impact of nicotine (through changes in smoke pH or through additives such as menthol) (Box 1) [3],[4]

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it's sandy and like that of clay with gray and red-brown colorations, and a low acidity