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Supply Chain Challenges : Lead times for raw materials like ABS plastic and copper have increased by 1520% since 2022

eSmoke brand e-liquids had the highest concentrations of the minor tobacco alkaloids (6.348.2 g/g nornicotine, 8.762.7 g/g myosmine, 21.2152 g/g anabasine, 63.1485 g/g anatabine, and 2.420.7 g/g isonicoteine)

When compared, a 20mg/ml vape, which has 40mg of nicotine, equates to smoking one to two packs of 20 cigarettes

However, the fundamental role of pyrazines in creating appealing tobacco flavours means that any combustible tobacco product will likely contain these compounds and their associated health risks

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