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Regardless of the method or frequency of smoking, the inhalation of tobacco smoke exposes the body to a wide range of toxic chemicals and carcinogens, leading to serious health consequences

One of the most important physiological effects of nicotine on the body is its ability to constrict blood vessels

One of history's most esoteric methods of satisfying a tobacco jones is making a resurgence as a new generation of hipsters trade lungs full of smoke for a nose full of snuff

because of this, it is sometimes confused with other tobacco products, namely dry snuff

Author contributions Y-TC, Z-JS, W-CS, and J-SW contributed to conception and design of the study