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Lorillard Tobacco Company touting its TV sponsorship by Kent and Newport cigarettes of the 1964 Summer Olympic Games

In addition to lungs, nicotine has profound systemic effects on many organs such as kidneys, heart, liver, and gastrointestinal tract, mediated through damage to epithelial, endothelial, and fibroblast cells [84]

Adapted from US Department of Health and Human Services, The Health Consequences of Smoking50 Years of Progress: A Report of the Surgeon General (Atlanta: 2014)

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