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In men, persistent infection can lead to epididymitis, which in a small number of cases can lead to infertility

5 Whether these companies are directly involved in smuggling is contentious, but what we can say is that they often deliberately leave their supply chains unsecured, making smuggling by other parties easier, says Dr Hana Ross, an expert on tobacco control and Principal Research Officer at the Economics of Excisable Products Research Unit at the University of Cape Town

With a high concentration of heroin and traces of Valium in his bloodstream, the medical examiner determined that, despite the desperate hunt to find him, Cobains body had been lying there for about two days

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In Brazil, production stopped in 2019