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In this situation, a multiple source drug in an NDA may become a single source drug if all its other therapeutically equivalent drugs are discontinued and the now-single source NDA is later shifted into a separately payable code

We maintained the data completeness criteria threshold of at least 75 percent for the CY 2026 performance period/2028 MIPS payment year (88 FR 79334 through 79337)

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Gallagher et al [138] found no significant variation in DNA adduct levels in sperm from heavy smokers (20 cigarettes/d), light smokers ( A of NAT2 can therefore be used as a novel genetic marker for susceptibility to idiopathic male infertility, but the risk is potentiated by exposure to various environmental oxidants, including cigarette smoke