Studying lung cancer in this way, three different studies have identified a location on the long arm of chromosome 15 where genetic variation greatly increases or decreases the likelihood of smokers becoming addicted to nicotine and of developing lung cancer (the researchers disagree whether the two likelihoods are linked)
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doi: 10.1111/apa.12791
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The Institute of Medicine said the benefit to public health depends on the degree to which local and state governments change their policies. Overall, in the absence of transformative changes in the tobacco market, social norms and attitudes, or in the knowledge of patterns and causes of tobacco use, the committee is reasonably confident that raising the (minimum legal age) will reduce tobacco use initiation, particularly among adolescents 15 to 17 years of age
