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Ann Intern Med 133(8):635646

185 During platelet activation, AGs secrete multiple bioactive molecules involved in key cellular functions like adhesion proteins, 186,187 growth factors, 188,189 cytokines and chemokines, 190,191,192,193,194,195 clotting factors and inhibitors, 196,197,198,199,200 membrane proteins, 56,201,202,203,204,205 complement components, 206 and proteases and protease inhibitors 207,208,209,210,211,212,213,214 (Table 2)