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Heatmap showing the relative ion intensities (z-scores) of selected metabolites identified in the metabolomics analysis described in (A), highlighting pathways involved in glycolysis and the pentose phosphate pathway (PPP), the TCA cycle, pyrimidine synthesis, glutathione (GSH) metabolism, and creatine metabolism

Wilcoxon matched-pairs signed rank test was used between week 4, week 11 and week 19 to confirm the trajectories of each pattern

The ABCDEs of skin cancer stand for the following: Asymmetry : Common moles are typically symmetrical in shape, while skin cancer is usually asymmetrical

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