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15 Patients usually begin one to two weeks before their quit date, with a one week dose escalation period, followed by 11 weeks of maintenance treatment:* 15 Step 1 set a quit date Step 2 initiate varenicline one to two weeks before this quit date, initially at a dose of 500 micrograms, once daily, for the first three days Step 3 increase the dose to 500 micrograms, twice daily, for four days Step 4 increase the dose to 1 mg, twice daily Step 5 most patients should continue with this maintenance dose for 11 weeks

Surfaces may be painted to trap odor, although it may be possible for odors to gradually seep through paint barriers