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Interestingly, when we treated cancer cells with CM collected from nicotine-treated fibroblast (MRC-5), we did not observe any changes in EMT/MET markers, whereas nicotine-treated monocytes (THP1) CM increased E-cadherin expression to a lesser extent (Supplementary Fig

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Kaufman didn't consider himself a comedian, so part of the humor of his "stand-up" involved the audience, expecting to hear or see something funny, waiting impatiently for a joke that would never come or a punchline that made no sense