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Though nicotine can make your heart race and temporarily boost blood pressure, its the non-nicotine components of tobacco smoke that are thought to damage and harden blood vessels, says Holly Middlekauff, a cardiologist at the Ronald Reagan UCLA Medical Center

In October 2024, British American Tobacco (BAT) launched a new line of synthetic nicotine pouches, in what would be seen as a significant technological advancement in the oral nicotine segment

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