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Cancers (Basel) 2020

Further, the guidance states that NRT drug products that have demonstrated effectiveness for cessation or reduction in risk of relapse may include information in the labeling regarding how quitting smoking can lower a persons chances of having lung disease, heart disease, and the risk of getting certain types of cancer that are related to smoking, without providing additional data

Slow and cumbersome regulatory processes that cannot keep pace with technological innovation

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The largest uncertainty is the future regulation of nicotine analogues, particularly 6-methyl nicotine, or 6-MN