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To determine whether SLC25A39 transport function is essential for GSH import into mitochondria, we generated a homology model of SLC25A39 based on that of the bovine ADP/ATP transporter 19 that facilitated the identification of three potential substrate binding residues, K329, M133 and D226 (Fig

Current studies highlight its potential as a selective model compound, though outcomes remain exploratory and require further inquiry to clarify mechanisms and implications

Melanocyte-specific CD8+ T cells are associated with epidermal depigmentation in a novel mouse model of vitiligo

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Nat Rev Clin Oncol 6 : 587595