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Following applying hemin for 18 h, the supernatant was collected and transferred to 96-well plates to detect LDH release

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Here, we compare the effects of ketamine and thiopental anesthetics with each other and with a non-anesthetized control group

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Mechanistically, these effects are linked to GLP-1 RA-mediated suppression of inflammatory pathways, modulation of skeletal muscle metabolism, and preservation of mitochondrial function, thereby influencing insulin resistance