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From the window outside my cubicle, I was face to face with video billboard playing the painfully hip new commercial from the e-cigarette company Juul

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Moreover, even by itself, nicotine is a sympathomimetic drug that elicits hemodynamic and metabolic changes that could increase the risk of acute cardiovascular events such as arrhythmias or plaque rupture and chronically increase cardiovascular disease risk by inducing dyslipidemia