Life Sci 272:119241 Hassanein EH, Shalkami A-GS, Khalaf MM, Mohamed WR, Hemeida RA (2019) The impact of Keap1/Nrf2, P38MAPK/NF-B and Bax/Bcl2/caspase-3 signaling pathways in the protective effects of berberine against methotrexate-induced nephrotoxicity
Aging Aging is accompanied by the progressive loss of anatomical structure and physiological function of the body (organs, tissues, and cells) leading to age-related diseases such as cardiovascular (atherosclerosis, stroke, etc.), musculoskeletal (sarcopenia and osteoporosis), neurodegenerative (dementia, etc.), immunological (arthritis, inflammaging and metainflammation), endocrine/metabolism diseases (diet, obesity and insulin resistance, etc.), gastrointestinal disorders (irritable bowel, celiac disease, etc.), and various cancers
They target dark circles, puffiness, and fine lines, while regulating the skins moisture-oil balance
Maintaining a balanced gut microbiome is crucial for hormonal harmony, stable mood, efficient metabolism, and overall vitality
Nevertheless, GSH is commonly used as a liver-protective drug after chemotherapy for breast cancer patients to mitigate chemotherapy-induced hepatotoxicity
