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A randomized clinical trial published in May 2026 in The Lancet investigated whether semaglutide, a GLP-1 peptide that acts as a GLP-1 receptor agonist and is approved for obesity treatment, was associated with changes in alcohol consumption among adults living with both obesity and alcohol use disorder

These studies have been consistently and repeatedly confirmed in both human and rodent brain, and many of the rates are tabulated by Hertz (2011b)

doi: 10.1016/j.physbeh.2024.114793, 80 KimW.EganJ

Not recommended for pregnant or breast-feeding women or adolescents