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The most direct comparison to Wegovy comes from the SURMOUNT-5 trial, which put tirzepatide and semaglutide head-to-head for the first time

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Cardiovascular Outcomes# LEADER Trial (Liraglutide)# The LEADER trial (Marso et al., NEJM 2016) enrolled 9,340 patients with type 2 diabetes and high cardiovascular risk

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Down-regulated miR-16-2 in peripheral blood is positively correlated with decreased bilateral insula volume in patients with major depressive disorder