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Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry

But only for a short period of time, and when you come down, youre dumber than you were before taking that first sip (unless you drink more coffee!)

Influence of inhaled nicotine source on arterial stiffness

On the other hand, while vaping is not without its risks, it is widely regarded as a less harmful alternative to smoking, and the long-term health impacts of vaping are still being studied

The rise and fall of nicotine concentration was matched by the smoking urge response, with a rapid decrease in urge followed by a gradual return toward baseline