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Patients with depression with higher baseline inflammation also respond more poorly to serotonergic antidepressants such as SSRIs compared with nonserotonergic antidepressants that modulate dopamine neurotransmission, such as nortriptyline and bupropion (Uher et al., 2014
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Free Radic Biol Med 53:437446
There is a worrying rise in depression among teenagers, who are 30 times more likely to commit suicide 12
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