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McCabe and colleagues analysed data from 61 observational studies conducted around the world between 1980 and 2014 that included nearly 15,000 tobacco users and over 273,000 non-users
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Four of the studies enrolled e-cigarettenave combustible tobacco cigarette smokers, nine studies enrolled experienced e-cigarette users, and one enrolled both groups
Some potentially harmful chemicals have been detected in e-cigarettes, namely nitrosamines, formaldehyde, acetaldehyde, acrolein, metals, and PAHs, which are known or suspected carcinogens