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Additionally, chronic supplementation has shown potential in ameliorating factors associated with metabolic syndrome and cardiovascular disease, such as arterial hypertension and impaired glucose tolerance.[13] A systematic review and meta-analysis further supports these findings, revealing that L-carnitine supplementation at doses of 13 g/day significantly reduced waist circumference, systolic blood pressure, fasting blood sugar, and triglycerides, while also increasing HDL cholesterol

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Endocrinology 150 , 26542659, (2009)