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Evidence from preclinical models suggests neurotoxic events and protracted consequences on cholinergic neurotransmission following nicotine exposure particularly during adolescence [7375]

If appropriate prevention strategies are not put in place to curb the number of young Americans who pick up smoking, an estimated 5.4 million people under the age of 18 will die prematurely due to a smoking-related illness

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The group I and group II users had diminished levels of urea clearance and there was a statistically significant difference in group I users but not in group II users than normal controls