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Moringa oleiferaA Functional Food and Its Potential Immunomodulatory Effects

We demonstrated that the accumulated fumarate leads to oxidative stress by covalently binding to reduced GSH in a non-enzymatic reaction that forms succinicGSH

Additional benefits have been observed in renal outcomes , with some GLP-1 agonists showing protective effects, primarily through reductions in albuminuria and a slower decline in estimated glomerular filtration rate (eGFR)

Besides, macrophages (M) in adipose tissue are also involved in IR and lead to the impairment of adipose tissue functions (122)

Its presence in various brain areas underscores its significance in neurobiology and neuromodulation, making it a subject of interest in research exploring its potential therapeutic applications [2]