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Thanks to years of successful tobacco control policies, including smoke-free air legislation, tobacco taxes, restrictions on youth marketing and access, and public health campaigns that denormalized smoking, the dramatic decline in the prevalence of smoking is considered one of the most successful public health efforts of the last century

These are practical issues that need continuous testing and transparent safety checks

29, 2013, with a random sample of 178,067 adults, aged 18 and older, living in all 50 U.S

If you werent smoking, you could be saving up for a new car, the down payment on your first home, or your dream vacation

Study selection and data extraction We included prospective cohorts with at least 50 cardiovascular disease events (mortality, morbidity, or both) to minimise the potential for reporting bias, in which large but unreliable effects might be seen in small studies