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In Nineteen Eighty-Four , Orwells dystopian masterpiece published just before he dies aged 46 in January 1950, the totalitarian nature of the state, forever intruding on the individual citizens private life, is symbolised with the face of the leader, Big Brother, appearing on everything books, banners, posters and cigarette wrappers (1976 [1949]: 758)

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Does Cigarette Smoking Affect Cervical Laminoplasty Clinical and Radiologic Outcomes

If the current trajectory continues, we risk further entrenching the black market, driving more people to unregulated and potentially dangerous products, and ultimately failing to achieve the desired public health outcomes

doi: 10.1210/en.2010-0855 149 JiaoZYWuJLiuCWenBZhaoWZDuXL