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DSIP vs melatonin Melatonin signals sleep timing to your circadian system but does not directly enhance sleep depth

10.1523/JNEUROSCI.2302-14.2015 J

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Addressing these questions will require time-resolved ubiquitin proteomics and tissue-specific in vivo loss-of-function studies across circadian timepoints to understand how the UPS both encodes and responds to circadian signals at the molecular level